Results At 6 months, levels of LDL-C were significantly lower in intervention participants (mean difference, −5 mg/dL P = .04). Secondary end points included systolic blood pressure, body mass index (BMI), physical activity, and smoking status. Main Outcomes and Measures The primary end point was low-density lipoprotein cholesterol (LDL-C) level at 6 months. Messages for each participant were selected from a bank of messages according to baseline characteristics (eg, smoking) and delivered via an automated computerized message management system. Patients in the control group (n=358) received usual care. Text messages provided advice, motivational reminders, and support to change lifestyle behaviors. Interventions Patients in the intervention group (n = 352) received 4 text messages per week for 6 months in addition to usual care. Objective To examine the effect of a lifestyle-focused semipersonalized support program delivered by mobile phone text message on cardiovascular risk factors.ĭesign and Setting The Tobacco, Exercise and Diet Messages (TEXT ME) trial was a parallel-group, single-blind, randomized clinical trial that recruited 710 patients (mean age, 58 years 82% men 53% current smokers) with proven coronary heart disease (prior myocardial infarction or proven angiographically) between September 2011 and November 2013 from a large tertiary hospital in Sydney, Australia. Mobile health strategies could address this gap but lack evidence of therapeutic benefit. Importance Cardiovascular disease prevention, including lifestyle modification, is important but underutilized. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.

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